unload is awesome for harassing healers, and missile blast is awesome for crappy AOE (when you need to stop a cap). I keep these two on crap keys, but still hittable if I need them (shift 5 and shift 6).
The only time unload belongs in PVE is when you're tanking and you won't get hit for the entire duration, but even then it's just a filler.
Heroic Moment and Shoulder Slam are the only two abilities that don't have a place on my bars; they are only useful for solo PVE (like dailies) and I don't really do solo PVE. They are ridiculously powerful abilities if you can use them, though.