Go tank spec and use whatever pet in dps spec. I was able to pretty much 2 or 3 shot every class boss up to Voss where it got a little more difficult. Pointers 1) Find the most efficient use of interrupts. Let's be honest, a lot of people just try to face roll and zerg the bosses and get frustrated when it doesn't work. For instance, I have the normal interrupt, spike, and electrocute so I use the kick, spike, kick, electrocute, kick, spike, kick and usually the mob dies. Deception has low slice too. 2) Figure out which spells are ok not to interrupt. You have to think and not just blindly interrupt. Light damage spells can be left alone, but things like chain lightning and the aoe lightning need to be interrupted on pretty much every class boss such as Zash. 3) 20 minute cooldown. Don't wait until you are almost dead. 75% ish seems to be a good marker for me and times in pretty solid with my interrupt rotation. 4) Use ALL your abilities and cooldowns. You can't just spam thrash and hope to win. 5) Get out of AoE's. It's a dynamic game. Don't take shots to the face that you can avoid.