I don't have the magic solution.
I play with no over engineered mouse and still manage to be more than descent.
classic move bind like i'm playing a fps
1 macro (with a software)
1,2,3,4,5 caps 1,2,3,4,5 and ctrl 1,2,3
F1 F2 F3 (A,E,R,T,F,G)
My left hand is very busy (japanese piano player envie this left hand)
and my mouse control the camera and Turning
It's not suitable for everybody