Here's my issues:
1) Droids aren't dropping the Isotope
2) He teleports me about 100 feet away, I can Force-Sprint out of the room, but it's a long run back (the teleport occurs just before he fires the laser)
3) Missles. I can get underneath him to DPS, but once I step out to attack the droids I get bounced around like a pinball
4) Companion, using Talos for heals, but he too gets teleported away then plinks at the boss with his pistol (even though I've turned off every non heal ability)
I destroyed the first room, but now (to reiterate) the isotopes aren't dropping and I can't get to the second. May try just killing Droids and ignoring him for the most part. VERY frustrating.
EDIT: 5) Ignores my Assassin taunts