I'm running 2x gtx590s in SLI. For me it was between 285.62 and 295.73.
While I was running 285.62 the fans in my graphic cards would sometimes kick into high speed and my pc would immediately reboot. Most of the time my pc was left in a state where it would have to be manually powered off. I was forced to disable my SLI while using these drivers in game. With SLI disabled I had no issues with this driver.
I upgrade to 295.73 a day or two after it released. At first it seemed to fix all of the problem I was having. However, over the last few days, since Tuesday's patch, I have been getting artifacting and driver crashes.
I am currently using 295.51 beta, and I have issues to speak of at the moment.