I'm a recent convert from WoW which I played for about 5 yrs. For our class you do not need tons of bindings to be honest but a couple are necessary IMO.
As everyone suggested, I would get used to WASD for moving (mouse for directions).
LAYOUT
Next I will tell you about what I found working for me best.
I have 2bars up and 1 bar on the right. Right bar is not necessary for game play, it's mostly for stuff like vehicle, buffs, quicktravel etc.
Bottom CENTER bar I map from 1 to 6
1-> Force Slow
2-> Shock
3-> Lightning Strike
4-> Force Lightning
5-> electrocute
6-> Force Speed
3 is almost above 'W', and it's the spell I click the most (your filler spell).
Now above those I have my the exact same numbers with CTRL keys. I cannot use shift or alt, I tried but did not feel comfortable. However, CTRL is easy for me. so here is the layout of of regular BAR (above middle bottom)
CTRL+1 -> Heroic Moment: ... (difficult to reach and rarely used)
CTRL+2 -> Jolt (to interrupt)
CTRL+3 -> Recklessness
CTRL+4 -> Chain Lightning
CTRL+5 -> Force Storm
I cannot comfortable reach CTRL + anything else, so I dont use them. Instead I map the next keys to F keys, which are very easy to jump to, oncey ou have your left middle finger on '3' (so 2-3-4 the most commonly pressed ones)
F1 -> Choose companion (to quickly throw a heal, shield etc)
F2 -> Choose myself (to quickly throw a heal)
F3 -> Polarity Shift
F4 -> Relic for alacricity
F5 -> Dark Heal
I fill the rest of the bar on the right side with the stuff mapped to mouse buttons and I also use '-', '+', '*' keys
- -> Seethe
+ -> Medpac (like + HP)
* -> Dark Infusion
Mouse wheel up -> Crushing Darkness (my opening at fights)
Mouse wheel down -> Affliction (my send spell in rotation)
Mouse button 3 (press down wheel ) - > Whirldwind
Mouse button 4 -> Overload
Mouse button 5 -> Shield
Also have a binding for putting you companion to passive mode (to give up fighting and follow u) I use '7' on the right side of the keypad.
GAMEPLAY
I have all companions at this point, and already have a thread about which one to use when, you can check that out and learn what people find useful. At your level, Kem is da man.
Make sure you turn on options that show the HP of the mob (and yours). That way you get used to seeing what you can take down easily and which ones are difficult for you. To give you an example. I ave 10K HP, my companions also have around that and I can take down elites that are about 25-27K HP (a bit more than our total).
Make sure you have Full HP before fighting. Shield and send your companion to your target (if group, choose the strongest one that you do not CC), and start casting (mouse wheel up), (mouse hweel down), then use 3,4,5 accordingly. Once you get higher, you will usually send your companion and use AOE spell (Force Storm).
If you feel that fight is not going well, you will die, sprint away. let your companion keep fighting. When (s)he dies, do not resurrect. Dismiss and call back (comes back as full HP).
Watch your enemy's cast bar. Interrupt whenever you can (CTRL+2/Jolt and '5'/Electrocute in my case).
Never wait for your spell to finish before casting the next. I.e. Do not hit 3, wait it to finish and hit 3 again. Instead hit 3, half way there start hitting 3 repeatedly until the next spell starts (check out Game > Controls > Ability Action Queue Window and tinker with it)
Well, there are tons of others things to mention but hopefully this gives you an idea... good luck
