I'm in the same boat with color blindness. Shades of reds and greens are hard to see with both eyes, and my left eye is going fast, meaning almost everything is grayscale with a small hint of color that is hard to distinguish. My main areas are the Nameplates above enemies, floating combat text (dmg/heals), Orange gear would give me an issue, but thankfully its usually empty or lets me know I can put mods in it with the ctrl+right click text. Some menu items in the crafting list are also a pain. Oh and of course the targeting reticule should be thicker or more noticeable.