Lol, I know this all too well. Although, I've noticed over the last 2 1/2 years or so, people have calmed down and now I rarely get the "OMG GIRL!1!!!!!1" thing on vent and in game.
When I first started playing MMOs, oh geez, a decade ago, I used to get really offended when I would be referred to as "he." That ended after about 6months though, now I just accept my virtual sex change and go with it.
I kind of enjoy the excitement in a vent server when people realize I'm female, I've heard some of my favorite pick up lines from it XD
Its the guys that go way overboard and get too explicit I have issues with. Fortunately, I'm pretty much always with my husband, so he's right there to tell them to back off and if I'm not with him, I'm with my guildies who I've known for years now and they take on the big brother role and chase off anyone bugging me.