I went synthweaving and it has been going pretty well. 50-75% of my armor is stuff that I have made, or has been dropped in a FP or Heroic. But I have also been able to make armor for those who have just joined our guild, so I am also able to help them out. Right now I am saving for that license, so I have not done much in it, but once I hit lvl 25 and drop 40k, I'll be once again investing into it heavily.
My hope is that I will be able to make gear that is compatable with raid end drops, or at least close to. And if that doesn't work, I certainly hope to be able to make money off of it. So I am not to worried about it. Right now, though, I like it, and was making gear that was two levels higher than I was at the time.