That's 2 completely different things rolled into one.
Yes, it does work. I run VMware Fusion with Win7 on my iMac at work. With all the settings on low it's more than playable.
Yes, there are issues with the mouse.
So who left... Me...
Well, I'm half way out the door tbh. Just re-subbed to RIFT for 3 months. Holy crap that client is so silky smooth. FPS nice and consistent, forgotten what it felt like to play an nicely optimised game